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Keith
Neeves
Assistant Professor
B.S.
University of Colorado, Boulder
Ph.D. Cornell University
Post-Doctoral study at University of Pennsylvania
Drug Delivery, Microfluidics
Publications
Contact Information
Research
Description
My research focuses on
the study and treatment of neurological and neurovascular diseases. Specifically, I am
interested in the development of therapies which target both extracellular
and cellular components of blood clots, the neurovasculature, and the
brain. My approach is to use microsystems as a tool for both developing in
vitro models of disease and developing new drug delivery devices. The
aim of in vitro models is to relate measureable properties,
such as hydraulic permeability, to features of the extracellular matrix
(ECM), such as porosity, pore size, and fiber diameter. In addition,
new strategies for manipulating the ECM to enhance drug transport are
investigated within these models. The strategies developed in model
systems are then applied to the design of devices for controlling the
spatial and temporal distribution of drugs in vivo.
Contact
Information
Keith Neeves
Chemical Engineering Dept.
Colorado School of Mines
Golden, CO 80401
FAX: (303) 273-3730
kneeves@mines.edu
