Sciex x500R QToF

Sciex x500R QToF

fei helios nanolab in use


Coolbaugh Hall, Room 325


Erin Sedlacko –


Instrument Details

Liquid Chromatography-Mass Spectrometry is an analytical technique for determining an ion’s mass-to-charge ratio by partitioning the particles within a liquid and measuring the time it takes for each particle to travel through a selected mobile phase.  Ultimately this helps in determining the contents of a liquid sample and can be used to analyze biochemical, organic and inorganic compounds.

A Quadrupole Time-of-Flight Mass Spectrometer is a very sensitive system which can be very beneficial in non-target analysis involving screening a sample for a multitude of unknown compounds.  Similar to a Triple Quad MS, there are three quadrupoles arranged in a series.  A QToF MS switches out the third quadrupole for a TOF mass analyzer, allowing for greater range of ion detection and mass accuracy.  Using a QToF system makes it possible to perform a full ion scan to allow for future analysis of unknown compounds without needing to reacquire data.