Project Info

Expanding Data Storage in DNA Through Unnatural Base Pairs

Mike McGuirk
cmmcguirk@mines.edu
DNA has been proposed as a long term data storage medium. Yet, the density of data storage possible is limited by there only being two base pairs in native DNA. Through the synthesis of new nucleobases and base pairs, we aim to enhance the data storage density of DNA, thereby making DNA a more desirable data storage medium.

More Information:

Grand Challenge: Engineer better medicines
https://www.mcguirk-supra-mat-chem.com/ https://en.wikipedia.org/wiki/DNA_digital_data_storage https://www.youtube.com/watch?v=aPWA-n9oo4k&ab_channel=SimplyExplained

Primary Contacts:

Mike McGuirk Brian Eckstein (post doc)

Student Preparation

Qualifications

taken organic chemistry and organic chemistry lab

TIME COMMITMENT (HRS/WK)

6-8

SKILLS/TECHNIQUES GAINED

synthetic chemistry analytical chemistry experiment design research ethics

MENTORING PLAN

The student's project will be guided by Prof. McGuirk and Dr. Brian Eckstein (post-doc). Dr. Eckstein will provide hands-on supervision, guidance and training in the lab.

PREFERRED STUDENT STATUS

Sophomore
Junior
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